{"id":10599,"date":"2021-12-15T17:20:57","date_gmt":"2021-12-15T17:20:57","guid":{"rendered":"https:\/\/research.christianacare.org\/publications\/2021\/12\/15\/adjustment-of-high-flow-nasal-cannula-rates-using-real-time-work-of-breathing-indices-in-premature-infants-with-respiratory-insufficiency\/"},"modified":"2021-12-15T17:20:57","modified_gmt":"2021-12-15T17:20:57","slug":"adjustment-of-high-flow-nasal-cannula-rates-using-real-time-work-of-breathing-indices-in-premature-infants-with-respiratory-insufficiency","status":"publish","type":"post","link":"https:\/\/research.christianacare.org\/publications\/2021\/12\/15\/adjustment-of-high-flow-nasal-cannula-rates-using-real-time-work-of-breathing-indices-in-premature-infants-with-respiratory-insufficiency\/","title":{"rendered":"Adjustment of high flow nasal cannula rates using real-time work of breathing indices in premature infants with respiratory insufficiency"},"content":{"rendered":"

Kovatis KZ, Locke RG, Mackley AB, Subedi K, Shaffer TH<\/p>\n

J Perinatol 2021 07;41(7):1711-1717<\/p>\n

PMID: 33664469<\/a><\/p>\n

Abstract<\/h2>\n

OBJECTIVE”>To assess the feasibility of real-time monitoring of work of breathing (WOB) indices and the impact of adjusting HFNC flow on breathing synchrony and oxygen stability in premature infants.<\/Abstr:<\/strong> To assess the feasibility of real-time monitoring of work of breathing (WOB) indices and the impact of adjusting HFNC flow on breathing synchrony and oxygen stability in premature infants.<\/p>\n

STUDY DESIGN”>A prospective, observational study of infants stable on HFNC. The flow adjusted per predetermined algorithm. Respiratory inductive plethysmography (RIP) noninvasively measured WOB. A high-resolution pulse oximeter collected oxygen saturation and heart rate data. Summary statistics and mixed linear models were used.<\/Abstr:<\/strong> A prospective, observational study of infants stable on HFNC. The flow adjusted per predetermined algorithm. Respiratory inductive plethysmography (RIP) noninvasively measured WOB. A high-resolution pulse oximeter collected oxygen saturation and heart rate data. Summary statistics and mixed linear models were used.<\/p>\n

RESULTS”>Baseline data for 32 infants, final analysis of 21 infants. Eighty-one percent with abnormal WOB. Sixty-two percent demonstrated 20% improvement in WOB. For infants with gestational age <28 weeks, an incremental increase in HFNC flow rate decreased WOB (p\u2009<\u20090.001) and improved oxygen saturation and stability (p\u2009<\u20090.01).<\/Abstr:<\/strong> Baseline data for 32 infants, final analysis of 21 infants. Eighty-one percent with abnormal WOB. Sixty-two percent demonstrated 20% improvement in WOB. For infants with gestational age <28 weeks, an incremental increase in HFNC flow rate decreased WOB (p\u2009<\u20090.001) and improved oxygen saturation and stability (p\u2009<\u20090.01).<\/p>\n

CONCLUSIONS”>Premature infants do not receive optimal support on HFNC. The use of a real-time feedback system to adjust HFNC is feasible and improves WOB, oxygen saturation, and oxygen stability. This technology may improve the utility of HFNC in premature infants.\u00a9 2021. The Author(s), under exclusive licence to Springer Nature America, Inc. part of Springer Nature.<\/CopyrightInfo:<\/strong> Premature infants do not receive optimal support on HFNC. The use of a real-time feedback system to adjust HFNC is feasible and improves WOB, oxygen saturation, and oxygen stability. This technology may improve the utility of HFNC in premature infants.<\/p><\/p>\n","protected":false},"excerpt":{"rendered":"

Kovatis KZ, Locke RG, Mackley AB, Subedi K, Shaffer TH J Perinatol 2021 07;41(7):1711-1717 PMID: 33664469 Abstract OBJECTIVE”>To assess the feasibility of real-time monitoring of work of breathing (WOB) indices and the impact of adjusting HFNC flow on breathing synchrony and oxygen stability in premature infants.<\/Abstr: To assess the feasibility of real-time monitoring of work<\/p>\n

Continue reading Adjustment of high flow nasal cannula rates using real-time work of breathing indices in premature infants with respiratory insufficiency<\/span><\/a><\/p>\n","protected":false},"author":0,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[41],"tags":[],"class_list":["post-10599","post","type-post","status-publish","format-standard","hentry","category-ireach"],"acf":[],"_links":{"self":[{"href":"https:\/\/research.christianacare.org\/publications\/wp-json\/wp\/v2\/posts\/10599","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/research.christianacare.org\/publications\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/research.christianacare.org\/publications\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/research.christianacare.org\/publications\/wp-json\/wp\/v2\/comments?post=10599"}],"version-history":[{"count":0,"href":"https:\/\/research.christianacare.org\/publications\/wp-json\/wp\/v2\/posts\/10599\/revisions"}],"wp:attachment":[{"href":"https:\/\/research.christianacare.org\/publications\/wp-json\/wp\/v2\/media?parent=10599"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/research.christianacare.org\/publications\/wp-json\/wp\/v2\/categories?post=10599"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/research.christianacare.org\/publications\/wp-json\/wp\/v2\/tags?post=10599"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}