Adverse Pregnancy Outcomes among Women with Prior Spontaneous or Induced Abortions

Makhlouf MA, Clifton RG, Roberts JM, Myatt L, Hauth JC, Leveno KJ, Varner MW, Thorp JM, Mercer BM, Peaceman AM, Ramin SM, Iams JD, Sciscione A, Tolosa JE, Sorokin Y, Am J Perinatol 2013 Dec; PMID: 24347257 Abstract Objective The aim of the article is to determine whether prior spontaneous abortion (SAB) or induced abortion (IAB),

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Interactive questioning in critical care during handovers: a transcript analysis of communication behaviours by physicians, nurses and nurse practitioners

Rayo MF, Mount-Campbell AF, O’Brien JM, White SE, Butz A, Evans K, Patterson ES BMJ Qual Saf 2014 Jun;23(6):483-9 PMID: 24336577 Abstract OBJECTIVE: Although there is a growing recognition of the importance of active communication behaviours from the incoming clinician receiving a patient handover, there are currently no agreed-upon measures to objectively describe those behaviours.

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Health status and quality of life in patients with stable coronary artery disease and chronic kidney disease treated with optimal medical therapy or percutaneous coronary intervention (post hoc findings from the COURAGE trial)

Sedlis SP, Jurkovitz CT, Hartigan PM, Kolm P, Goldfarb DS, Lorin JD, Dada M, Maron DJ, Spertus JA, Mancini GB, Teo KK, Boden WE, Weintraub WS, Am. J. Cardiol. 2013 Dec;112(11):1703-8 PMID: 24011740 Abstract Chronic kidney disease (CKD) is an important clinical co-morbidity that increases the risk of death and myocardial infarction in patients with

Continue reading Health status and quality of life in patients with stable coronary artery disease and chronic kidney disease treated with optimal medical therapy or percutaneous coronary intervention (post hoc findings from the COURAGE trial)

Thyroid function in late preterm infants in relation to mode of delivery and respiratory support

Behme RM, Mackley AB, Bartoshesky L, Paul DA J. Pediatr. Endocrinol. Metab. 2013 Nov;:1-6 PMID: 24259241 Abstract Abstract The relationship between thyroid function, mode of delivery, and illness in infants 34-36 weeks’ gestation has not been well studied. We hypothesized that infants born by cesarean delivery and those with increased illness would have a reduction

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Transfusing neonates based on platelet count vs. platelet mass: A randomized feasibility-pilot study

Zisk JL, Mackley A, Clearly G, Chang E, Christensen RD, Paul DA Platelets 2013 Nov; PMID: 24224920 Abstract Abstract The objective of this study was to obtain pilot data on which to judge the feasibility and sample size needed for a future comparative-effectiveness trial of platelet transfusions in the NICU. We conducted a limited-scope pilot

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Influence of surgical and minimally invasive facial cosmetic procedures on psychosocial outcomes: a systematic review

Imadojemu S, Sarwer DB, Percec I, Sonnad SS, Goldsack JE, Berman M, Sobanko JF JAMA Dermatol 2013 Nov;149(11):1325-33 PMID: 24068036 Abstract IMPORTANCE: Millions of surgical and minimally invasive cosmetic procedures of the face are performed each year, but objective clinical measures that evaluate surgical procedures, such as complication rates, have limited utility when applied to

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Recommendations for the design of Phase 3 pharmaceutical trials that are more informative for patients, clinicians, and payers

Sonnad SS, Mullins CD, Whicher D, Goldsack JC, Mohr PE, Tunis SR Contemp Clin Trials 2013 Nov;36(2):356-61 PMID: 23999501 Abstract BACKGROUND: Pharmaceutical pragmatic clinical trials (PCTs) are designed to provide the type of evidence that is desired by patients, clinicians and payers but too often missing from traditional regulatory trials. PURPOSE: This paper presents framework

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Myositis ossificans of the temporalis muscle: case report and review of the literature

Schiff MJ, Meara DJ J. Oral Maxillofac. Surg. 2013 Nov;71(11):1893-8 PMID: 23871468 Abstract Myositis ossificans, also known as traumatic myositis ossificans or myositis ossificans circumscripta, is the product of an unusual reactive process of mesenchymal stem cells within the muscle produced secondary to a traumatic insult or inflammatory process. In approximately 75% of cases, the

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Management of bleeding and reversal strategies for oral anticoagulants: clinical practice considerations

Nutescu EA, Dager WE, Kalus JS, Lewin JJ, Cipolle MD Am J Health Syst Pharm 2013 Nov;70(21):1914-29 PMID: 24128967 Abstract PURPOSE: Currently available clinical data and optimal strategies for reversing oral anticoagulants in patients who are bleeding or need an urgent invasive procedure or operation are reviewed. SUMMARY: Bleeding from oral anticoagulants, including new target-specific

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Cerebrovascular autoregulation and neurologic injury in neonatal hypoxic-ischemic encephalopathy

Howlett JA, Northington FJ, Gilmore MM, Tekes A, Huisman TA, Parkinson C, Chung SE, Jennings JM, Jamrogowicz JJ, Larson AC, Lehmann CU, Jackson E, Brady KM, Koehler RC, Lee JK Pediatr. Res. 2013 Nov;74(5):525-35 PMID: 23942555 Abstract BACKGROUND: Neonates with hypoxic-ischemic encephalopathy (HIE) are at risk of cerebral blood flow dysregulation. Our objective was to

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