Durability of class I American College of Cardiology/American Heart Association clinical practice guideline recommendations

Neuman MD, Goldstein JN, Cirullo MA, Schwartz JS JAMA 2014 May;311(20):2092-100 PMID: 24867012 Abstract IMPORTANCE: Little is known regarding the durability of clinical practice guideline recommendations over time. OBJECTIVE: To characterize variations in the durability of class I (“procedure/treatment should be performed/administered”) American College of Cardiology/American Heart Association (ACC/AHA) guideline recommendations. DESIGN, SETTING, AND PARTICIPANTS:

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US veterans use vitamins and supplements as substitutes for prescription medication

Goldstein JN, Long JA, Arevalo D, Ibrahim SA, Mao JJ Med Care 2014 Dec;52(12 Suppl 5):S65-9 PMID: 25397826 Abstract BACKGROUND: Vitamins and supplements are the most commonly used form of complementary and alternative medicine in the United States. Growing research suggests that patients substitute vitamins and supplements for their prescription medications. The reasons might include

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Outcomes with advanced versus basic life support in blunt trauma

Farrell MS, Emery B, Caplan R, Getchell J, Cipolle M, Bradley KM Am. J. Surg. 2020 Jan; PMID: 32000980 Abstract INTRODUCTION: The role of advanced life support (ALS) versus basic life support (BLS) in blunt trauma is controversial. Previous studies have shown no mortality benefit with ALS for penetrating trauma but the blunt population has

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Health Care Hotspotting – A Randomized, Controlled Trial

Finkelstein A, Zhou A, Taubman S, Doyle J N. Engl. J. Med. 2020 01;382(2):152-162 PMID: 31914242 Abstract BACKGROUND: There is widespread interest in programs aiming to reduce spending and improve health care quality among “superutilizers,” patients with very high use of health care services. The “hotspotting” program created by the Camden Coalition of Healthcare Providers

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Impact of an external ventricular drain bundle and limited duration antibiotic prophylaxis on drain-related infections and antibiotic resistance

Whyte C, Alhasani H, Caplan R, Tully AP Clin Neurol Neurosurg 2019 Dec;190:105641 PMID: 31869626 Abstract BACKGROUND/OBJECTIVE: Systemic prophylactic antibiotics have been used to reduce the rate of neurosurgical drain-related infections (DRIs) but the optimal duration is unknown. The Neurocritical Care Society Consensus Statement for External Ventricular Drain (EVD) management recommends a single antibiotic dose

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Development of a Multidisciplinary Medical Home Program for NICU Graduates

Feehan K, Kehinde F, Sachs K, Mossabeb R, Berhane Z, Pachter LM, Brody S, Turchi RM Matern Child Health J 2019 Nov; PMID: 31745836 Abstract OBJECTIVE: Typical primary care practices are often not equipped to meet the medical, developmental or social needs of infants discharged from a neonatal intensive care unit (NICU). These needs are

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Even Faster Door-to-Alteplase Times and Associated Outcomes in Acute Ischemic Stroke

Jung S, Rosini JM, Nomura JT, Caplan RJ, Raser-Schramm J J Stroke Cerebrovasc Dis 2019 Dec;28(12):104329 PMID: 31607439 Abstract BACKGROUND AND PURPOSE: The timely administration of thrombolytic therapy for acute ischemic stroke has been associated with good functional outcomes. Current guidelines recommend alteplase administration within 60 minutes in 75% of eligible patients and within 45

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