Rivera-Torres N, Kmiec EB J Vis Exp 2017 Aug;(126) PMID: 28872131 Abstract Combinatorial gene editing using CRISPR/Cas9 and single-stranded oligonucleotides is an effective strategy for the correction of single-base point mutations, which often are responsible for a variety of human inherited disorders. Using a well-established cell-based model system, the point mutation of a single-copy mutant
Category: Publications & Presentations
Observation Status, Poverty, and High Financial Liability Among Medicare Beneficiaries
Goldstein JN, Zhang Z, Schwartz JS, Hicks LS Am. J. Med. 2018 Jan;131(1):101.e9-101.e15 PMID: 28774801 Abstract BACKGROUND: Medicare beneficiaries hospitalized under observation status are subject to cost-sharing with no spending limit under Medicare Part B. Because low-income status is associated with increased hospital use, there is concern that such beneficiaries may be at increased risk
Application of a Theoretical Model Toward Understanding Continued Food Insecurity Post Hurricane Katrina
Clay LA, Papas MA, Gill K, Abramson DM Disaster Med Public Health Prep 2018 Feb;12(1):47-56 PMID: 28758601 Abstract OBJECTIVE: Disaster recovery efforts focus on restoring basic needs to survivors, such as food, water, and shelter. However, long after the immediate recovery phase is over, some individuals will continue to experience unmet needs. Ongoing food insecurity
The Importance of Inclusion for Cardiovascular Health Promotion Programs in Delaware
Papas MA, Stolz N, Orsega-Smith E, Sparling E, Freedman B Health Promot Pract 2018 Mar;19(2):256-266 PMID: 28573871 Abstract Individuals with disabilities experience greater rates of cardiovascular disease than individuals without disabilities. This increase can be attributed to decreased levels of physical activity, poor eating habits, and increased levels of diabetes, smoking, and obesity. Individuals with
APPLYING HUMAN FACTORS ENGINEERING TO IMPROVE USABILITY AND WORKFLOW IN PATHOLOGY INFORMATICS
Mount-Campbell AF, Hosseinzadeh D, Gurcan M, Patterson ES Proc Int Symp Hum Factors Ergon Healthc 2017 Jun;6(1):23-27 PMID: 30073176 Abstract Human factors engineering is an underutilized approach in the design, evaluation, and implementation of health information technology. Heuristic evaluation of the usability of an interface is a ‘low-hanging fruit’ for identifying a set of relatively
Importance of engaging obstetrician/gynecologists in cardiovascular disease prevention
Ehrenthal DB, Catov JM Curr. Opin. Cardiol. 2013 Sep;28(5):547-53 PMID: 23928919 Abstract PURPOSE OF REVIEW: To review recent evidence regarding traditional and sex-specific factors identified among women during their reproductive years and their importance in lifetime risk for cardiovascular disease (CVD). RECENT FINDINGS: Longitudinal studies demonstrated a woman’s burden of risk during her reproductive years
The people in your neighborhood: impact of physician cohorting on nursing units
Lyons D, Painter J, Crannell C, Mooney R, Bucher L, Joseph R, Schwandt C, Siano S, Marandola B, Keiser S, Bayne L Medsurg Nurs 2013 Sep-Oct;22(5):281-9, 302 PMID: 24358568 Abstract In a study exploring the impact of a new physician practice model on staff’s perceptions of their work environment, no statistically significant differences were found;
Continue reading The people in your neighborhood: impact of physician cohorting on nursing units
Variation in NICU Admission Rates Without Identifiable Cause
Ziegler KA, Paul DA, Hoffman M, Locke R Hosp Pediatr 2016 May;6(5):255-60 PMID: 27117951 Abstract OBJECTIVES: Admission to the NICU is influenced by physiologic compromise and by hospital care protocols. Providing appropriate care must be balanced with adverse consequences of NICU admission, such as interrupting maternal-infant bonding and unnecessary interventions. This study aims to determine
Continue reading Variation in NICU Admission Rates Without Identifiable Cause
Determining the magnitude of surveillance bias in the assessment of lower extremity deep venous thrombosis: A prospective observational study of two centers
Shackford SR, Cipolle MD, Badiee J, Mosby DL, Knudson MM, Lewis PR, McDonald VS, Olson EJ, Thompson KA, Van Gent JM, Zander AL J Trauma Acute Care Surg 2016 May;80(5):734-9; discussion 740-1 PMID: 26891155 Abstract BACKGROUND: Venous thromboembolism (VTE) remains a significant cause of morbidity and mortality in trauma. Controversy exists regarding the use of
Predicting violent behavior in clinical settings: a case-control study of a mental health inpatient unit
Miller KE, Benden ME, Shipp EM, Pickens AW, Wendel ML, Pronovost PJ, Watts BV J Healthc Prot Manage 2016;32(1):106-19 PMID: 26978965 Abstract In order to assist staff in recognizing patients prone to violence and guide their clinical decision-making, this study summarizes mental health inpatient unit incidents over a one-year period. Results describe demographic and clinical