Category: Topics

Assembling and Analyzing Cohorts from Electronic Health Records: An Example from the NICU

Electronic health records (EHR) contain a wealth of information potentially useful for public health research, and can be used to assemble retrospective cohorts for epidemiological analyses. This presentation demonstrates the experience of the Neonatology Division of the Department of Pediatrics to create a research dataset from the neonatal intensive care unit (NICU) EHR. We then […]

Applied Genomics: Next Generation Sequencing in the Clinical Field

Acute myeloid leukemia (AML) is a disease of the genome involving many genetic alterations for disease onset. Using next generation sequencing (NGS) data generated by the NCI TARGET project from pediatric AML patients, we have developed a novel pipeline for detection of SNVs and structural variants with enhanced data integration, visualization, and prioritization scoring to […]