Category: Topics

What CAN Be Done About the Cost of Care for Chronic Diseases and Conditions

The annual cost of care in the United States for people with chronic diseases accounts for more that 83 percent ($1.2 trillion) of all healthcare costs – and this cost continues to rise. Yet many chronic diseases and conditions are linked to lifestyle choices so they can be prevented. This presentation will review the current […]

Assembling and Analyzing Cohorts from Electronic Health Records: An Example from the NICU

Electronic health records (EHR) contain a wealth of information potentially useful for public health research, and can be used to assemble retrospective cohorts for epidemiological analyses. This presentation demonstrates the experience of the Neonatology Division of the Department of Pediatrics to create a research dataset from the neonatal intensive care unit (NICU) EHR. We then […]

Applied Genomics: Next Generation Sequencing in the Clinical Field

Acute myeloid leukemia (AML) is a disease of the genome involving many genetic alterations for disease onset. Using next generation sequencing (NGS) data generated by the NCI TARGET project from pediatric AML patients, we have developed a novel pipeline for detection of SNVs and structural variants with enhanced data integration, visualization, and prioritization scoring to […]