Category: Research, Design, and Statistics

Differences in Patient and Physician Perceptions of Care for Patients with Myeloproliferative Neoplasms

This talk will focus on data collected from the Landmark Survey, a large survey of patients with myeloproliferative neoplasms (MPNs, namely essential thrombocytosis, primary myelofibrosis, and polycythemia vera) and the providers who take care of patients with MPNs. The Landmark Survey focused on quality of life issues surrounding the diagnosis of MPNs and differences in […]

Engineering Mayo Clinic’s Care Delivery

The healthcare sector is facing major challenges with regards to quality and access to care. The Institute of Medicine and the National Academy of Engineering proposed a medicine-engineering partnership to address these challenges. Mayo Clinic’s Kern Center for the Science of Health Care Delivery hosts the Information and Decision Engineering program that translates research and […]

Privacy-Protecting Technologies for Collaborative Research

The rapid increase in digitized information related to human health has raised the possibility of performing more complex statistical analyses by pooling data from several different sources or institutions. This presentation will discuss modern approaches for sharing access to private data to give clinicians and researchers an overview of how these technologies work, what the […]

Delaware Medical Legal Partnership: Attorneys Collaborating with Clinical Teams to Address Social Determinants of Health

Patients challenged with social determinants of health are more likely to incur higher health care costs due to their inability to adhere to prescribed medical recommendations and their inefficient use of health care resources. Some of these challenges can be resolved with legal intervention. The Medical-Legal Partnership (MLP) model has demonstrated positive impact on improving […]

Preventing Perioperative Cardiovascular Complications: The Conundrum Continues

Perioperative cardiovascular complications or major adverse cardiovascular events (MACEs), including all-cause death, myocardial infarction (MI), cardiac arrest, stroke and repeat revascularization either by PCI or CABG, remain the leading cause of postoperative complications and death among the aged patients (≥ 45 years old) undergoing major noncardiac surgery. Meanwhile, based on the ACC/AHA guidelines on perioperative […]

The Translational Informatics Infrastructure in South Carolina

The Biomedical Informatics Center (BMIC) at MUSC was established as a program in 2008 as part of research infrastructure development and investment by MUSC and Health Sciences South Carolina (HSSC). The BMIC includes a dedicated team of Informatics faculty and staff who work on research and operations projects across the state. The team has been […]

Implementing a Mid-Trial Adaptation in a Stroke Clinical Trial: The Good, The Bad and the Ugly

The use of adaptive designs has been increasing in randomized clinical trials. Sample size re-estimation is a type of adaptation in which nuisance parameters are estimated at an interim point in the trial and the sample size re-computed based on these estimates. However, post-hoc evaluations of the adaptation, including sample size re-estimation, have not frequently […]

Faculty Mentoring in Challenging Times

These are challenging times in academic medicine – faculty are under enormous pressure to generate more revenue through clinical care or grant funding in very competitive environments at the same time that administrative demands and regulatory requirements keep increasing. This has made it increasingly difficult for faculty to find time to teach and maintain scholarly […]

Kids Safe and Smokefree: A Multilevel Intervention Model to Address Child Tobacco Smoke Exposure and Parental Smoking in Underserved Communities

Low-income and underserved populations have higher smoking rates, greater challenges in quitting smoking, and bear greater tobacco-related morbidity/mortality risk than the general population. More intensive interventions are needed to address this ongoing public health priority. This presentation will describe a recently completed trial that combined a pediatric systems-level intervention with a pragmatic, individualized intervention. We […]

The Role of Mentorship in Research

Mentoring is widely recognized as a critical pillar in the development of researchers, but significant challenges exist in clinical and translational science. This presentation will discuss some of these challenges, how they are being addressed in different academic settings across the country, and how institutions in Delaware are working together to develop infrastructure and programs […]