Social constraints and fear of recurrence in couples coping with early stage breast cancer

Soriano EC, Pasipanodya EC, LoSavio ST, Otto AK, Perndorfer C, Siegel SD, Laurenceau JP Health Psychol 2018 Sep;37(9):874-884 PMID: 30138023 Abstract OBJECTIVE: Fear of cancer recurrence (FCR) is a top concern of breast cancer (BC) survivors and their spouses. FCR often occurs within an interpersonal context, yet there has been little research on relationship processes

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Assessing the relationship between fear of cancer recurrence and health care utilization in early-stage breast cancer survivors

Otto AK, Soriano EC, Siegel SD, LoSavio ST, Laurenceau JP J Cancer Surviv 2018 Oct; PMID: 30341560 Abstract PURPOSE: The purpose of this study was to determine whether fear of cancer recurrence (FCR) is associated with greater health care utilization (HCU) in early-stage breast cancer survivors. METHODS: Three hundred early-stage breast cancer survivors diagnosed within

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Does sharing good news buffer fear of bad news? A daily diary study of fear of cancer recurrence in couples approaching the first mammogram post-diagnosis

Soriano EC, Perndorfer C, Otto AK, Siegel SD, Laurenceau JP Psychooncology 2018 Jun; PMID: 29927016 Abstract OBJECTIVE: The core of fear of cancer recurrence (FCR)-a top concern of couples after successful breast cancer (BC) treatment-is fear of death. Daily relationship processes may be instrumental in regulating FCR as triggers of existential distress are encountered. We

Continue reading Does sharing good news buffer fear of bad news? A daily diary study of fear of cancer recurrence in couples approaching the first mammogram post-diagnosis

Checking Behavior, Fear of Recurrence, and Daily Triggers in Breast Cancer Survivors

Soriano EC, Valera R, Pasipanodya EC, Otto AK, Siegel SD, Laurenceau JP Ann Behav Med 2018 May; PMID: 29771272 Abstract Background: Fear of cancer recurrence (FCR) is a top ongoing concern of breast cancer (BC) survivors and thus the focus of recent intervention development. The Self-Regulation Model of FCR (Lee-Jones C, Humphris G, Dixon R,

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Cost-effectiveness of a standard intervention versus a navigated intervention on colorectal cancer screening use in primary care

Lairson DR, Dicarlo M, Deshmuk AA, Fagan HB, Sifri R, Katurakes N, Cocroft J, Sendecki J, Swan H, Vernon SW, Myers RE Cancer 2014 Apr;120(7):1042-9 PMID: 24435411 Abstract BACKGROUND: Colorectal cancer (CRC) screening is cost-effective but underused. The objective of this study was to determine the cost-effectiveness of a mailed standard intervention (SI) and tailored

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Tadalafil for prevention of erectile dysfunction after radiotherapy for prostate cancer: the Radiation Therapy Oncology Group [0831] randomized clinical trial

Pisansky TM, Pugh SL, Greenberg RE, Pervez N, Reed DR, Rosenthal SA, Mowat RB, Raben A, Buyyounouski MK, Kachnic LA, Bruner DW JAMA 2014 Apr;311(13):1300-7 PMID: 24691606 Abstract IMPORTANCE: Tadalafil is used to treat erectile dysfunction after prostate cancer treatment, but its role as a preventive agent is undefined. OBJECTIVES: To determine primarily whether tadalafil

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Hyaluronan: A simple polysaccharide with diverse biological functions

Dicker KT, Gurski LA, Pradhan-Bhatt S, Witt RL, Farach-Carson MC, Jia X Acta Biomater 2014 Apr;10(4):1558-1570 PMID: 24361428 Abstract Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the extracellular matrix (ECM), on the cell surface and even inside cells. Being a

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A novel in vivo model for evaluating functional restoration of a tissue-engineered salivary gland

Pradhan-Bhatt S, Harrington DA, Duncan RL, Farach-Carson MC, Jia X, Witt RL Laryngoscope 2014 Feb;124(2):456-61 PMID: 23832678 Abstract OBJECTIVES/HYPOTHESIS: To create a novel model for development of a tissue-engineered salivary gland from human salivary gland cells that retains progenitor cell markers useful for treatment of radiation-induced xerostomia. STUDY DESIGN: A three-dimensional (3D) hyaluronic acid (HA)-based

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Combined KIT and FGFR2b Signaling Regulates Epithelial Progenitor Expansion during Organogenesis

Lombaert IM, Abrams SR, Li L, Eswarakumar VP, Sethi AJ, Witt RL, Hoffman MP Stem Cell Reports 2013;1(6):604-19 PMID: 24371813 Abstract Organ formation and regeneration require epithelial progenitor expansion to engineer, maintain, and repair the branched tissue architecture. Identifying the mechanisms that control progenitor expansion will inform therapeutic organ (re)generation. Here, we discover that combined

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