Tadalafil for prevention of erectile dysfunction after radiotherapy for prostate cancer: the Radiation Therapy Oncology Group [0831] randomized clinical trial

Pisansky TM, Pugh SL, Greenberg RE, Pervez N, Reed DR, Rosenthal SA, Mowat RB, Raben A, Buyyounouski MK, Kachnic LA, Bruner DW JAMA 2014 Apr;311(13):1300-7 PMID: 24691606 Abstract IMPORTANCE: Tadalafil is used to treat erectile dysfunction after prostate cancer treatment, but its role as a preventive agent is undefined. OBJECTIVES: To determine primarily whether tadalafil

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Hyaluronan: A simple polysaccharide with diverse biological functions

Dicker KT, Gurski LA, Pradhan-Bhatt S, Witt RL, Farach-Carson MC, Jia X Acta Biomater 2014 Apr;10(4):1558-1570 PMID: 24361428 Abstract Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the extracellular matrix (ECM), on the cell surface and even inside cells. Being a

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Ankyloglossia its impact breastfeeding

Henry L, Hayman R Nurs Womens Health 2014 Apr;18(2):122-9 PMID: 24750651 Abstract This article contrasts two very different experiences of one mother breastfeeding her two sons to demonstrate the potential impact of ankyloglossia on breastfeeding. When too restrictive, ankyloglossia, also known as tongue-tie, can cause the newborn to ineffectively suckle at the breast. Breastfeeding difficulties

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Ultrasound-guidance can reduce adverse events during femoral central venous cannulation

Powell JT, Mink JT, Nomura JT, Levine BJ, Jasani N, Nichols WL, Reed J, Sierzenski PR J Emerg Med 2014 Apr;46(4):519-24 PMID: 24462032 Abstract BACKGROUND: Ultrasound-guidance for internal jugular central venous cannulation (CVC) has become the recommended best practice and has been shown to improve placement success and reduce complications. There is a dearth of

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Impact of shortages of injectable oncology drugs on patient care

Goldsack JC, Reilly C, Bush C, McElligott S, Bristol MN, Motanya UN, Field R, Vozniak JM, Wong YN, Schwartz JS, Domchek S Am J Health Syst Pharm 2014 Apr;71(7):571-8 PMID: 24644117 Abstract PURPOSE: Results of a survey regarding shortages of injectable oncology drugs in U.S. hospitals and health systems are presented. METHODS: An online survey

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Prescriber Perceptions of a Pediatric Antimicrobial Stewardship Program

Flannery DD, Swami S, Chan S, Eppes S Clin Pediatr (Phila) 2014 Mar;53(8):747-750 PMID: 24676643 Abstract Antimicrobial stewardship programs (ASPs) can help improve antimicrobial use in hospitals and, therefore, reduce resistance. Our hospital implemented an ASP in 2004, with interventions based on Infectious Diseases Society of America recommendations. We aimed to assess the perceived effectiveness

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Patient Satisfaction Surveys and Quality of Care: An Information Paper

Farley H, Enguidanos ER, Coletti CM, Honigman L, Mazzeo A, Pinson TB, Reed K, Wiler JL Ann Emerg Med 2014 Mar; PMID: 24656761 Abstract With passage of the Patient Protection and Affordable Care Act of 2010, payment incentives were created to improve the “value” of health care delivery. Because physicians and physician practices aim to

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