A Quantitative Model for Glagov Remodeling in Atherosclerosis

Glagov phenomenon describes how atherosclerotic vessels change shape under an increasing disease burden (see Glagov et al, New England Journal of Medicine 1987). Specifically, lumen areas remain constant or increase slightly before contracting as intima areas increase. This presentation will introduce a mathematical model for Glagov remodeling and allow clinicians and researchers to understand the process in terms of the elastic properties of the vessel.

Dr. Pak-Wing Fok is an applied mathematician from the Department of Mathematical Sciences at the University of Delaware. He obtained his PhD from MIT in 2006 and from 2006-2009, held a Von Karman Instructorship at Caltech and a postdoctoral position in the Department of Biomathematics at UCLA. His research interests include mathematical biology, stochastic processes and operations research.


The Innovative Discoveries Series, sponsored by the Delaware Clinical & Translational Science ACCEL program and the Christiana Care Value Institute, features informal presentations on topics relevant to current research and healthcare practice, led by knowledgeable and experienced presenters. There are offerings for researchers, healthcare providers, and community members of varying levels of experience.

These free talks are held Fridays at noon at Christiana Hospital but can be viewed from your home or office computer. Earn CMEs by participating in-person or online. Lunch is served and all are welcome to attend.

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Contact Sarahfaye Dolman at sarahfaye.f.dolman@christianacare.org with any questions.

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