The Human Gut Microbiome and Health: Insights from System-Level Models

There has been a revolution in medical thinking based on the large number of diseases that have been associated with alterations in the composition of the human microbiome. Examples include autism, allergies, Inflammatory Bowel Diseases (IBD), diabetes, obesity, cardiovascular diseases, autoimmune diseases, and neurological disorders such as Autism Spectrum Disorders (ASD). A major research challenge is to see how one can dynamically manipulate and move the complex microbial system away from a disease state towards a healthy state. This talk will illustrate the important role of system-level models in the context of our research on ASD. Modeling tools from mathematics and artificial intelligence are used to obtain insights into the role of the human gut microbiome in health and disease.

Dr. Prasad Dhurjati is a Professor of Chemical & Biomolecular Engineering and Mathematical Sciences at the University of Delaware. His research specialization is in Biotechnology, Artificial Intelligence, and Systems Medicine. He is the author of over 100 research publications in leading journals with over 2400 citations. In 1986, he was awarded the National Science Foundation Presidential Young Investigator Award by President Ronald Reagan. In 2004, he was elected a Fellow of the American Institute of Medical and Biological Engineering. In 1988-89, he was a visiting scientist at the Pasteur Institute in Paris and he has also been a visiting professor at the University of Lyon, France, VNIT, India and University of Toronto, Canada.


The Innovative Discoveries Series, sponsored by the Delaware Clinical & Translational Science ACCEL program and the Christiana Care Value Institute, features informal presentations on topics relevant to current research and healthcare practice, led by knowledgeable and experienced presenters. There are offerings for researchers, healthcare providers, and community members of varying levels of experience.

These free talks are held Fridays at noon at Christiana Hospital but can be viewed from your home or office computer. Earn CMEs by participating in-person or online. Lunch is served and all are welcome to attend.

To see the full calendar of events, visit the Value Institute Events page or the ACCEL website, or subscribe to the ID Series mailing list.

Contact Sarahfaye Dolman at sarahfaye.f.dolman@christianacare.org with any questions.

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