Category: Topics

Value Institute Inaugural Symposium 2012 – “Value: Medicine’s New Frontier”

Senator Chris Coons has worked hard to find bipartisan solutions to the issues facing Delaware and the nation. He has emerged as a strong voice for job creation and the innovation economy, fighting in Congress for deficit reduction, progressive social justice, and forward-looking foreign policy. Unwilling to be sidelined by partisan gridlock, Chris has worked […]

Fear, Vulnerability, and Sacrifice as Factors in ED Use: Ethnographic Research Methods and their Insights

Ethnographic research and social analyses in healthcare settings have long been valued, however their use is not widespread. Qualitative research about patient-centered care makes patients the experts, and providers, policy makers and administrators the students. In this presentation, I discuss a 2015 case study of a 51-year-old low-income Philadelphia man who had two ED visits […]

Single Molecule DNA and RNA Sequencing to Detect Residual Cancer and Clonal Hematopoiesis

Dr. Druley will discuss novel strategies for single molecule DNA and RNA sequencing as a modality for characterization of clonal hematopoiesis and minimal residual disease (MRD) detection in cancer. Despite “deep sequencing,” next-generation platforms have an error rate of 0.5-1.0%, precluding straightforward sequencing for MRD, which requires sensitivity of less than 1:1,000. However, using a […]

Field Trials in Developing Countries: Lessons from the PURE Study

The PURE study assesses environmental, societal, and biological influences on obesity and chronic health conditions such as heart disease, diabetes, and cancer. This presentation will describe the setup and execution of this large and complex study; key findings to date; and the possibilities and pitfalls of field-based data collection in developing countries. Dr. Rahman is […]

Endothelial Function in Relatively Healthy Persons: Studies of the Old Order Amish

Endothelial cells are the first layer response to atherosclerotic risk factors. In clinically healthy individuals with no overt disease, Laser Doppler Flowmetry is used to evaluate endothelial function. This presentation will review endothelial cell response to clopidogrel and clopidogrels activation in the body. Last, we will review genetic determinants of endothelial growth factor angiopoietin-2, a […]

Differences in Patient and Physician Perceptions of Care for Patients with Myeloproliferative Neoplasms

This talk will focus on data collected from the Landmark Survey, a large survey of patients with myeloproliferative neoplasms (MPNs, namely essential thrombocytosis, primary myelofibrosis, and polycythemia vera) and the providers who take care of patients with MPNs. The Landmark Survey focused on quality of life issues surrounding the diagnosis of MPNs and differences in […]

Engineering Mayo Clinic’s Care Delivery

The healthcare sector is facing major challenges with regards to quality and access to care. The Institute of Medicine and the National Academy of Engineering proposed a medicine-engineering partnership to address these challenges. Mayo Clinic’s Kern Center for the Science of Health Care Delivery hosts the Information and Decision Engineering program that translates research and […]

Privacy-Protecting Technologies for Collaborative Research

The rapid increase in digitized information related to human health has raised the possibility of performing more complex statistical analyses by pooling data from several different sources or institutions. This presentation will discuss modern approaches for sharing access to private data to give clinicians and researchers an overview of how these technologies work, what the […]

Delaware Medical Legal Partnership: Attorneys Collaborating with Clinical Teams to Address Social Determinants of Health

Patients challenged with social determinants of health are more likely to incur higher health care costs due to their inability to adhere to prescribed medical recommendations and their inefficient use of health care resources. Some of these challenges can be resolved with legal intervention. The Medical-Legal Partnership (MLP) model has demonstrated positive impact on improving […]

Preventing Perioperative Cardiovascular Complications: The Conundrum Continues

Perioperative cardiovascular complications or major adverse cardiovascular events (MACEs), including all-cause death, myocardial infarction (MI), cardiac arrest, stroke and repeat revascularization either by PCI or CABG, remain the leading cause of postoperative complications and death among the aged patients (≥ 45 years old) undergoing major noncardiac surgery. Meanwhile, based on the ACC/AHA guidelines on perioperative […]