Imadojemu S, Sarwer DB, Percec I, Sonnad SS, Goldsack JE, Berman M, Sobanko JF JAMA Dermatol 2013 Nov;149(11):1325-33 PMID: 24068036 Abstract IMPORTANCE: Millions of surgical and minimally invasive cosmetic procedures of the face are performed each year, but objective clinical measures that evaluate surgical procedures, such as complication rates, have limited utility when applied to
Recommendations for the design of Phase 3 pharmaceutical trials that are more informative for patients, clinicians, and payers
Sonnad SS, Mullins CD, Whicher D, Goldsack JC, Mohr PE, Tunis SR Contemp Clin Trials 2013 Nov;36(2):356-61 PMID: 23999501 Abstract BACKGROUND: Pharmaceutical pragmatic clinical trials (PCTs) are designed to provide the type of evidence that is desired by patients, clinicians and payers but too often missing from traditional regulatory trials. PURPOSE: This paper presents framework
Myositis ossificans of the temporalis muscle: case report and review of the literature
Schiff MJ, Meara DJ J. Oral Maxillofac. Surg. 2013 Nov;71(11):1893-8 PMID: 23871468 Abstract Myositis ossificans, also known as traumatic myositis ossificans or myositis ossificans circumscripta, is the product of an unusual reactive process of mesenchymal stem cells within the muscle produced secondary to a traumatic insult or inflammatory process. In approximately 75% of cases, the
Management of bleeding and reversal strategies for oral anticoagulants: clinical practice considerations
Nutescu EA, Dager WE, Kalus JS, Lewin JJ, Cipolle MD Am J Health Syst Pharm 2013 Nov;70(21):1914-29 PMID: 24128967 Abstract PURPOSE: Currently available clinical data and optimal strategies for reversing oral anticoagulants in patients who are bleeding or need an urgent invasive procedure or operation are reviewed. SUMMARY: Bleeding from oral anticoagulants, including new target-specific
Cerebrovascular autoregulation and neurologic injury in neonatal hypoxic-ischemic encephalopathy
Howlett JA, Northington FJ, Gilmore MM, Tekes A, Huisman TA, Parkinson C, Chung SE, Jennings JM, Jamrogowicz JJ, Larson AC, Lehmann CU, Jackson E, Brady KM, Koehler RC, Lee JK Pediatr. Res. 2013 Nov;74(5):525-35 PMID: 23942555 Abstract BACKGROUND: Neonates with hypoxic-ischemic encephalopathy (HIE) are at risk of cerebral blood flow dysregulation. Our objective was to
American Association for the Surgery of Trauma Prevention Committee topical overview: National Trauma Data Bank, geographic information systems, and teaching injury prevention
Crandall M, Zarzaur B, Tinkoff G Am. J. Surg. 2013 Nov;206(5):709-13 PMID: 24016704 Abstract BACKGROUND: Injury is the leading cause of death for all Americans aged 1 to 35 years, and injury-related costs exceed $100 billion per year in the United States. Trauma centers can be important resources for risk identification and prevention strategies. The
Comparative effectiveness of revascularization strategies in stable ischemic heart disease: current perspective and literature review
Fanari Z, A Weiss S, Weintraub WS Expert Rev Cardiovasc Ther 2013 Oct;11(10):1321-36 PMID: 24138520 Abstract Percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) are established strategies for coronary revascularization in the setting of ischemic heart disease. Multiple randomized controlled trials and observational studies have compared the impact of the two modalities on
Feasibility, acceptability and preliminary effectiveness of patient advocates for improving asthma outcomes in adults
Apter AJ, Wan F, Reisine S, Bogen DK, Rand C, Bender B, Bennett IM, Gonzalez R, Priolo C, Sonnad SS, Bryant-Stephens T, Ferguson M, Boyd RC, Ten Have T, Roy J J Asthma 2013 Oct;50(8):850-60 PMID: 23800333 Abstract BACKGROUND: Asthmatic adults from low-income urban neighborhoods have inferior health outcomes which in part may be due
Million Hearts Delaware: collaborating to save a million hearts by 2017
Savoy M Del Med J 2013 Oct;85(10):307-9 PMID: 24475647 Abstract
Methodological recommendations for comparative research on the treatment of chronic wounds
Sonnad SS, Goldsack JC, Mohr P, Tunis S J Wound Care 2013 Sep;22(9):470-80 PMID: 24005781 Abstract OBJECTIVE: To provide specific recommendations to product developers and clinical researchers on the design of comparative effectiveness studies for the treatment of chronic wounds, specifically those pertaining to arterial and venous-disease related ulcers, diabetic foot ulcers, pressure ulcers and