Methodological recommendations for comparative research on the treatment of chronic wounds

Sonnad SS, Goldsack JC, Mohr P, Tunis S J Wound Care 2013 Sep;22(9):470-80 PMID: 24005781 Abstract OBJECTIVE: To provide specific recommendations to product developers and clinical researchers on the design of comparative effectiveness studies for the treatment of chronic wounds, specifically those pertaining to arterial and venous-disease related ulcers, diabetic foot ulcers, pressure ulcers and

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What students experienced: a narrative analysis of essays written by first-year medical students participating in a geriatrics home visit

O’Donnell L, Carson L, Forciea MA, Kinosian B, Shea J, Yudin J, Miller RK J Am Geriatr Soc 2013 Sep;61(9):1592-7 PMID: 23888907 Abstract OBJECTIVES: To develop a house call experience for first-year medical students introducing them to challenges that homebound, chronically ill elderly adults face. DESIGN: During the semester, two students were paired with a

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Prognostic importance of coronary anatomy and left ventricular ejection fraction despite optimal therapy: assessment of residual risk in the Clinical Outcomes Utilizing Revascularization and Aggressive DruG Evaluation Trial

Mancini GB, Hartigan PM, Bates ER, Chaitman BR, Sedlis SP, Maron DJ, Kostuk WJ, Spertus JA, Teo KK, Dada M, Knudtson M, Berman DS, Booth DC, Boden WE, Weintraub WS Am. Heart J. 2013 Sep;166(3):481-7 PMID: 24016497 Abstract BACKGROUND: It is unknown if baseline angiographic findings can be used to estimate residual risk of patients

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DNMT1 is regulated by ATP-citrate lyase and maintains methylation patterns during adipocyte differentiation

Londoño Gentile T, Lu C, Lodato PM, Tse S, Olejniczak SH, Witze ES, Thompson CB, Wellen KE Mol. Cell. Biol. 2013 Oct;33(19):3864-78 PMID: 23897429 Abstract During adipocyte differentiation, significant epigenomic changes occur in association with the implementation of the adipogenic program. We have previously shown that histone acetylation increases during differentiation in a manner dependent

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The Association between Parathyroid Hormone Levels and Hemoglobin in Diabetic and Nondiabetic Participants in the National Kidney Foundation’s Kidney Early Evaluation Program

Memon I, Norris KC, Bomback AS, Peralta C, Li S, Chen SC, McCullough PA, Whaley-Connell A, Jurkovitz C, Tamura MK, Saab G, Cardiorenal Med 2013 Jul;3(2):120-127 PMID: 23922552 Abstract BACKGROUND: Both anemia and secondary hyperparathyroidism are reflections of hormonal failure in chronic kidney disease (CKD). While the association of elevated levels of parathyroid hormone (PTH)

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Perioperative risk factors for adverse airway events in patients undergoing cleft palate repair

Jackson O, Basta M, Sonnad S, Stricker P, Larossa D, Fiadjoe J Cleft Palate Craniofac. J. 2013 May;50(3):330-6 PMID: 23083121 Abstract Objective :  To establish the incidence of perioperative airway complications in a large series of pediatric patients undergoing palatoplasty and to identify which specific patient, procedural, and provider factors are associated with increased risk

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