Nelson JA, Tchou J, Domchek S, Sonnad SS, Serletti JM, Wu LC J Plast Reconstr Aesthet Surg 2012 Nov;65(11):1481-9 PMID: 22640643 Abstract BACKGROUND: Utilization of bilateral prophylactic mastectomy (BPM) and reconstruction has increased secondary to numerous medical advances. The purpose of this study was to examine decision making in women electing this therapy to further
Weight status and perception of colorectal cancer risk
Bittner Fagan H, Sifri R, Wender R, Schumacher E, Reed JF J Am Board Fam Med 2012 Nov-Dec;25(6):792-7 PMID: 23136317 Abstract BACKGROUND: Obesity increases the risk of many cancers including colorectal cancer (CRC). METHODS: This is secondary data analysis of the 2010 National Health Interview Survey data. A total of 9360 obese and overweight participants,
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Quality of breast cancer care: perception versus practice
Bickell NA, Neuman J, Fei K, Franco R, Joseph KA J. Clin. Oncol. 2012 May;30(15):1791-5 PMID: 22493417 Abstract PURPOSE: Because insurers use performance and quality metrics to inform reimbursement, identifying remediable causes of poor-quality cancer care is imperative. We undertook this descriptive cohort study to assess key predictors of women’s perceived quality of their breast
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DNA damage response pathway and replication fork stress during oligonucleotide directed gene editing
Bonner M, Strouse B, Applegate M, Livingston P, Kmiec EB Mol Ther Nucleic Acids 2012 Apr;1:e18 PMID: 23343929 Abstract Single-stranded DNA oligonucleotides (ODNs) can be used to direct the exchange of nucleotides in the genome of mammalian cells in a process known as gene editing. Once refined, gene editing should become a viable option for
Trauma leadership: does perception drive reality?
Sakran JV, Finneman B, Maxwell C, Sonnad SS, Sarani B, Pascual J, Kim P, Schwab CW, Sims C J Surg Educ 2012 Mar-Apr;69(2):236-40 PMID: 22365872 Abstract INTRODUCTION: Leadership plays a key role in trauma team management and might affect the efficiency of patient care. Our hypothesis was that a positive relationship exists between the trauma
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Extended trimethoprim/sulfamethoxazole prophylaxis for implant reconstruction in the previously irradiated chest wall
Mirzabeigi MN, Lee M, Smartt JM, Jandali S, Sonnad SS, Serletti JM Plast. Reconstr. Surg. 2012 Jan;129(1):37e-45e PMID: 22186583 Abstract BACKGROUND: Patients who have undergone prior chest wall irradiation can present as challenging candidates for implant reconstruction because of troublesome rates of infectious complications. The issue of antibiotic prophylaxis remains controversial, and evidence-based postoperative strategies
Prevalence of financial conflicts of interest among panel members producing clinical practice guidelines in Canada and United States: cross sectional study
Neuman J, Korenstein D, Ross JS, Keyhani S BMJ 2011 Oct;343:d5621 PMID: 21990257 Abstract OBJECTIVE: To determine the prevalence of financial conflicts of interest among members of panels producing clinical practice guidelines on screening, treatment, or both for hyperlipidaemia or diabetes. DESIGN: Cross sectional study. SETTING: Relevant guidelines published by national organisations in the United
A writing group for female assistant professors
Sonnad SS, Goldsack J, McGowan KL J Natl Med Assoc 2011 Sep-Oct;103(9-10):811-5 PMID: 22364047 Abstract INTRODUCTION: The number of female medical school faculty being promoted and the speed at which they are promoted have not kept pace with their male counterparts at many institutions. One of the reasons is that these women are not publishing
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Systemic barriers to diabetes management in primary care: a qualitative analysis of Delaware physicians
Elliott DJ, Robinson EJ, Sanford M, Herrman JW, Riesenberg LA Am J Med Qual 2011 Jul-Aug;26(4):284-90 PMID: 21393616 Abstract Primary care providers deliver the majority of care for patients with diabetes. This article presents a qualitative analysis of systemic barriers to primary care diabetes management in the small office setting in Delaware. Grounded theory was
Improved survival after pulmonary metastasectomy for soft tissue sarcoma
Predina JD, Puc MM, Bergey MR, Sonnad SS, Kucharczuk JC, Staddon A, Kaiser LR, Shrager JB J Thorac Oncol 2011 May;6(5):913-9 PMID: 21750417 Abstract INTRODUCTION: Survival after pulmonary metastasectomy for soft tissue sarcoma (STS) has been lower than in osteosarcoma (14-40% versus 40-50%). With improved patient selection criteria and advanced chemotherapy agents, we hypothesized that
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