Tolstoy NS, Aized M, McMonagle MP, Holena DN, Pascual JL, Sonnad SS, Sims CA J. Surg. Res. 2013 Apr;180(2):232-7 PMID: 22683082 Abstract BACKGROUND: In the critically ill, mineralocorticoid deficiency (MD) is associated with greater disease severity, the development of acute renal insufficiency, and increased mortality. We hypothesized that severely injured trauma patients presenting with hemorrhagic
Continue reading Mineralocorticoid deficiency in hemorrhagic shock
Elliott DJ, Robinson EJ, Anthony KB, Stillman PL Popul Health Manag 2013 Apr;16(2):99-106 PMID: 23405873 Abstract Value-based insurance design (VBID) initiatives have been associated with modest improvements in adherence based on evaluations of administrative claims data. The objective of this prospective cohort study was to report the patient-centered outcomes of a VBID program that eliminated
Lin IC, Bergey M, Sonnad SS, Serletti JM, Wu LC Ann Plast Surg 2013 Mar;70(3):264-70 PMID: 23038147 Abstract BACKGROUND: The Wise pattern can be used in mastectomies to address the excess skin in the ptotic or hypertrophic breast; however, limitations include mastectomy flap necrosis (MFN) and poor shape. The vertical pattern can potentially reduce the
Forsythe LP, Rowland JH, Padgett L, Blaseg K, Siegel SD, Dingman CM, Gillis TA Psychooncology 2013 Sep;22(9):1953-62 PMID: 23436558 Abstract OBJECTIVE: Although the Institute of Medicine provided a vision for effective psychosocial care for cancer survivors, limited guidance exists regarding the essential components of comprehensive care or progressive steps for implementing each component. This paper
Sims CA, Isserman JA, Holena D, Sundaram LM, Tolstoy N, Greer S, Sonnad S, Pascual J, Reilly P J Trauma Acute Care Surg 2013 Jan;74(1):157-65; discussion 165-6 PMID: 23271091 Abstract BACKGROUND: Research investigating the resuscitation and management of unstable trauma patients is necessary to improve care and save lives. Because informed consent for research is
Grill E, Strong M, Sonnad SS, Sarani B, Pascual J, Collins H, Sims CA J. Surg. Res. 2013 Jan;179(1):132-7 PMID: 23043865 Abstract BACKGROUND: Hemorrhagic shock profoundly affects the neuroendocrine profile of trauma patients, and we hypothesized that massive resuscitation would negatively impact thyroid function. METHODS: A prospective, observational study investigating thyroid function in hypotensive trauma
Continue reading Altered thyroid function in severely injured patients
Myers RE, Bittner-Fagan H, Daskalakis C, Sifri R, Vernon SW, Cocroft J, Dicarlo M, Katurakes N, Andrel J Cancer Epidemiol. Biomarkers Prev. 2013 Jan;22(1):109-17 PMID: 23118143 Abstract BACKGROUND: This randomized, controlled trial assessed the impact of a tailored navigation intervention versus a standard mailed intervention on colorectal cancer screening adherence and screening decision stage (SDS).
Lombaert IM, Abrams SR, Li L, Eswarakumar VP, Sethi AJ, Witt RL, Hoffman MP Stem Cell Reports 2013;1(6):604-19 PMID: 24371813 Abstract Organ formation and regeneration require epithelial progenitor expansion to engineer, maintain, and repair the branched tissue architecture. Identifying the mechanisms that control progenitor expansion will inform therapeutic organ (re)generation. Here, we discover that combined
Borjigin M, Strouse B, Niamat RA, Bialk P, Eskridge C, Xie J, Kmiec EB Mol Ther Nucleic Acids 2012 Dec;1:e59 PMID: 23212298 Abstract Gene editing is a process by which single base mutations can be corrected, in the context of the chromosome, using single-stranded oligodeoxynucleotides (ssODNs). The survival and proliferation of the corrected cells bearing
Nelson JA, Tchou J, Domchek S, Sonnad SS, Serletti JM, Wu LC J Plast Reconstr Aesthet Surg 2012 Nov;65(11):1481-9 PMID: 22640643 Abstract BACKGROUND: Utilization of bilateral prophylactic mastectomy (BPM) and reconstruction has increased secondary to numerous medical advances. The purpose of this study was to examine decision making in women electing this therapy to further